Swiss Biotechnology

BioPlatform: The Delivery Engine

Patented cargo loading and surface functionalization methods enabling safe, repeatable delivery of genetic medicines to previously unreachable tissues — including the brain.

95%
Genetic diseases
untreatable today
2
Patented delivery
methods
1
Patent
granted
BioPlatform Logo

The delivery problem in gene therapy

Of ~8,000 identified genetic diseases, only ~5% have approved treatments. The rest remain untreatable — not because we lack therapies, but because we cannot deliver them.

  • 1

    AAV Vectors

    No re-dosing possible, immunogenic response

  • 2

    Lipid Nanoparticles (LNP)

    Liver-only targeting, poor CNS penetration

  • 3

    Antisense Oligonucleotides

    Invasive intrathecal delivery required

95%
of genetic diseases remain
untreatable due to delivery limitations

Two patented delivery methods

Proprietary cargo loading and surface functionalization methods that solve the two key bottlenecks in nanovesicle-based gene therapy.

BP-1

EMNV Technology

Exosome-Mimetic Nanovesicles
  • Proprietary extrusion-based cargo loading method
  • Universal protein & RNP packaging
  • Zero immunogenicity, repeat dosing
  • Target: Hepatitis D (PoC complete)
Patent Granted
BP-2

Hybrid Technology

Biological NV + Synthetic Liposomes
  • Hybrid fusion method — 650x improved RNA loading
  • Surface functionalization for targeted delivery
  • Blood-brain barrier penetration & CNS targeting
  • Target: Huntington's Disease (Lead)
Patent Pending

Why BioPlatform

Our proprietary cargo loading and functionalization methods overcome key limitations of current delivery technologies.

Feature AAV LNP BioPlatform
BBB Penetration Moderate Poor Excellent
Repeat Dosing No Yes Yes
Immunogenicity High Moderate No
Cargo Loading Efficiency Low Moderate 650x improved
IV Administration Yes Yes Yes

Pipeline

Advancing multiple programs across CNS and liver indications.

Indication Platform Stage Status
Huntington's Disease BP-2 Hybrid Preclinical Planning LEAD PROGRAM
Hepatitis B BP-2 Hybrid PoC in Mouse Method Patent Mar 2026
Hepatitis D BP-1 EMNV PoC Complete Seeking Licensee
APOL1 Kidney Disease BP-2 Hybrid Research Back-up Indication

Get in Touch

Interested in partnership opportunities, licensing discussions, or investment? We'd love to hear from you.

Kira Hofmann — CEO & Founder
kira@bioplatform.ch
Zurich, Switzerland